Severity: 8192
Message: Creation of dynamic property CI_URI::$config is deprecated
Filename: core/URI.php
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Message: Creation of dynamic property CI_Router::$uri is deprecated
Filename: core/Router.php
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Message: Creation of dynamic property Welcome::$benchmark is deprecated
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Message: Creation of dynamic property Welcome::$hooks is deprecated
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Message: Creation of dynamic property Welcome::$log is deprecated
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Message: Creation of dynamic property Welcome::$exceptions is deprecated
Filename: core/Controller.php
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Message: Creation of dynamic property Welcome::$router is deprecated
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Message: Creation of dynamic property Welcome::$security is deprecated
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Message: Creation of dynamic property Welcome::$lang is deprecated
Filename: core/Controller.php
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Message: Creation of dynamic property Welcome::$load is deprecated
Filename: core/Controller.php
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Severity: 8192
Message: Creation of dynamic property Welcome::$db is deprecated
Filename: core/Loader.php
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Severity: 8192
Message: Creation of dynamic property CI_DB_mysqli_driver::$failover is deprecated
Filename: database/DB_driver.php
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Severity: 8192
Message: Creation of dynamic property Welcome::$form_validation is deprecated
Filename: core/Loader.php
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Message: Return type of CI_Session_files_driver::open($save_path, $name) should either be compatible with SessionHandlerInterface::open(string $path, string $name): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 132
Severity: 8192
Message: Return type of CI_Session_files_driver::close() should either be compatible with SessionHandlerInterface::close(): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
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Message: Return type of CI_Session_files_driver::read($session_id) should either be compatible with SessionHandlerInterface::read(string $id): string|false, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
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Message: Return type of CI_Session_files_driver::write($session_id, $session_data) should either be compatible with SessionHandlerInterface::write(string $id, string $data): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
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Message: Return type of CI_Session_files_driver::destroy($session_id) should either be compatible with SessionHandlerInterface::destroy(string $id): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
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Message: Return type of CI_Session_files_driver::gc($maxlifetime) should either be compatible with SessionHandlerInterface::gc(int $max_lifetime): int|false, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
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Severity: Warning
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Filename: Session/Session.php
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Severity: Warning
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Filename: Session/Session.php
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Message: Creation of dynamic property Welcome::$session is deprecated
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Message: Creation of dynamic property Welcome::$curl is deprecated
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Published : 05 Oct 2020
Drug Name: Coronavirus Disease 2019 (COVID-19) vaccine
Fujifilm has concluded a manufacturing contract agreement with biotechnology company VLP Therapeutics Japan for the latter’s Covid-19 vaccine formulation.
Fujifilm will use its manufacturing facilities and lipid nanoparticle infrastructure to manage activities associated with VLP’s Covid-19 vaccine formulations, including process development and production for clinical trials.
The product is a self-amplifying (replicon) RNA vaccine that uses a lipid nanoparticle formulation, a type of Drug Delivery System (DDS) technology.
The Japan Agency for Medical Research and Development (AMED) funding selected the vaccine project.
In Japan, VLP will take forward pre-clinical and clinical trials of the vaccine.
VLP will work with the National Center for Global Health and Medicine, the National Institutes of Biomedical Innovation, Health and Nutrition, Oita University, and Osaka City University.
In March, Fujifilm entered into a strategic partnership deal with Canada’s Precision NanoSystems (PNI).
Under the partnership, Fujifilm will leverage its 701 Factory with PNI’s NanoAssemblr technology and customer base for process development and contract manufacturing business.
In a separate development, NeuroRx and Swiss company Relief Therapeutics signed supply chain agreements and ordered enough drug substances of potential Covid-19 drug, RLF-100 (aviptadil), to treat one million patients.
Ref-100 is currently in Phase II / III clinical trials for treating critical Covid-19 patients in the US, with study data expected this month.
Furthermore, European trials of the drug should begin in the first quarter of next year.
NeuroRx CEO and chairman Dr. Jonathan Javitt said: “In normal circumstances, it would be prudent to wait until all the data are in before initiating commercial scale-up.
“However, in an environment where more than 40,000 Americans are contracting Covid-19 daily and 800 are dying each day, there is not a moment to lose in ensuring that sufficient quantities of RLF-100 will be available, should the clinical trials succeed in proving safety and efficacy.”
In June, the US Food and Drug Administration granted fast track designation to RLF-100 to treat acute lung injury / acute respiratory distress syndrome caused by Covid-19.
Source: GlobalData.com
