Severity: 8192
Message: Creation of dynamic property CI_URI::$config is deprecated
Filename: core/URI.php
Line Number: 101
Severity: 8192
Message: Creation of dynamic property CI_Router::$uri is deprecated
Filename: core/Router.php
Line Number: 127
Severity: 8192
Message: Creation of dynamic property Welcome::$benchmark is deprecated
Filename: core/Controller.php
Line Number: 75
Severity: 8192
Message: Creation of dynamic property Welcome::$hooks is deprecated
Filename: core/Controller.php
Line Number: 75
Severity: 8192
Message: Creation of dynamic property Welcome::$config is deprecated
Filename: core/Controller.php
Line Number: 75
Severity: 8192
Message: Creation of dynamic property Welcome::$log is deprecated
Filename: core/Controller.php
Line Number: 75
Severity: 8192
Message: Creation of dynamic property Welcome::$utf8 is deprecated
Filename: core/Controller.php
Line Number: 75
Severity: 8192
Message: Creation of dynamic property Welcome::$uri is deprecated
Filename: core/Controller.php
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Severity: 8192
Message: Creation of dynamic property Welcome::$exceptions is deprecated
Filename: core/Controller.php
Line Number: 75
Severity: 8192
Message: Creation of dynamic property Welcome::$router is deprecated
Filename: core/Controller.php
Line Number: 75
Severity: 8192
Message: Creation of dynamic property Welcome::$output is deprecated
Filename: core/Controller.php
Line Number: 75
Severity: 8192
Message: Creation of dynamic property Welcome::$security is deprecated
Filename: core/Controller.php
Line Number: 75
Severity: 8192
Message: Creation of dynamic property Welcome::$input is deprecated
Filename: core/Controller.php
Line Number: 75
Severity: 8192
Message: Creation of dynamic property Welcome::$lang is deprecated
Filename: core/Controller.php
Line Number: 75
Severity: 8192
Message: Creation of dynamic property Welcome::$load is deprecated
Filename: core/Controller.php
Line Number: 78
Severity: 8192
Message: Creation of dynamic property Welcome::$db is deprecated
Filename: core/Loader.php
Line Number: 390
Severity: 8192
Message: Creation of dynamic property CI_DB_mysqli_driver::$failover is deprecated
Filename: database/DB_driver.php
Line Number: 371
Severity: 8192
Message: Creation of dynamic property Welcome::$form_validation is deprecated
Filename: core/Loader.php
Line Number: 1290
Severity: 8192
Message: Return type of CI_Session_files_driver::open($save_path, $name) should either be compatible with SessionHandlerInterface::open(string $path, string $name): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 132
Severity: 8192
Message: Return type of CI_Session_files_driver::close() should either be compatible with SessionHandlerInterface::close(): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 290
Severity: 8192
Message: Return type of CI_Session_files_driver::read($session_id) should either be compatible with SessionHandlerInterface::read(string $id): string|false, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 164
Severity: 8192
Message: Return type of CI_Session_files_driver::write($session_id, $session_data) should either be compatible with SessionHandlerInterface::write(string $id, string $data): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 233
Severity: 8192
Message: Return type of CI_Session_files_driver::destroy($session_id) should either be compatible with SessionHandlerInterface::destroy(string $id): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 313
Severity: 8192
Message: Return type of CI_Session_files_driver::gc($maxlifetime) should either be compatible with SessionHandlerInterface::gc(int $max_lifetime): int|false, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 354
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 284
Severity: Warning
Message: session_set_cookie_params(): Session cookie parameters cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 291
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 306
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
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Severity: Warning
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Filename: Session/Session.php
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Filename: Session/Session.php
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Filename: Session/Session.php
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Severity: Warning
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Filename: Session/Session.php
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Severity: Warning
Message: session_set_save_handler(): Session save handler cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 110
Severity: Warning
Message: session_start(): Session cannot be started after headers have already been sent
Filename: Session/Session.php
Line Number: 143
Severity: 8192
Message: Creation of dynamic property Welcome::$session is deprecated
Filename: core/Loader.php
Line Number: 1290
Severity: 8192
Message: Creation of dynamic property Welcome::$curl is deprecated
Filename: core/Loader.php
Line Number: 1290
Severity: 8192
Message: Creation of dynamic property Welcome::$Reports_model is deprecated
Filename: core/Loader.php
Line Number: 353
Severity: 8192
Message: Creation of dynamic property Welcome::$User_model is deprecated
Filename: core/Loader.php
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Severity: 8192
Message: Creation of dynamic property Welcome::$data is deprecated
Filename: controllers/Welcome.php
Line Number: 11
Severity: 8192
Message: Creation of dynamic property Welcome::$pagination is deprecated
Filename: core/Loader.php
Line Number: 1290
Severity: 8192
Message: Creation of dynamic property CI_Loader::$benchmark is deprecated
Filename: core/Loader.php
Line Number: 925
Severity: 8192
Message: Creation of dynamic property CI_Loader::$hooks is deprecated
Filename: core/Loader.php
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Severity: 8192
Message: Creation of dynamic property CI_Loader::$config is deprecated
Filename: core/Loader.php
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Severity: 8192
Message: Creation of dynamic property CI_Loader::$log is deprecated
Filename: core/Loader.php
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Severity: 8192
Message: Creation of dynamic property CI_Loader::$utf8 is deprecated
Filename: core/Loader.php
Line Number: 925
Severity: 8192
Message: Creation of dynamic property CI_Loader::$uri is deprecated
Filename: core/Loader.php
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Severity: 8192
Message: Creation of dynamic property CI_Loader::$exceptions is deprecated
Filename: core/Loader.php
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Message: Creation of dynamic property CI_Loader::$router is deprecated
Filename: core/Loader.php
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Severity: 8192
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Filename: core/Loader.php
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Message: Creation of dynamic property CI_Loader::$security is deprecated
Filename: core/Loader.php
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Message: Creation of dynamic property CI_Loader::$input is deprecated
Filename: core/Loader.php
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Message: Creation of dynamic property CI_Loader::$lang is deprecated
Filename: core/Loader.php
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Message: Creation of dynamic property CI_Loader::$load is deprecated
Filename: core/Loader.php
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Severity: 8192
Message: Creation of dynamic property CI_Loader::$db is deprecated
Filename: core/Loader.php
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Severity: 8192
Message: Creation of dynamic property CI_Loader::$form_validation is deprecated
Filename: core/Loader.php
Line Number: 925
Severity: 8192
Message: Creation of dynamic property CI_Loader::$session is deprecated
Filename: core/Loader.php
Line Number: 925
Severity: 8192
Message: Creation of dynamic property CI_Loader::$curl is deprecated
Filename: core/Loader.php
Line Number: 925
Severity: 8192
Message: Creation of dynamic property CI_Loader::$Reports_model is deprecated
Filename: core/Loader.php
Line Number: 925
Severity: 8192
Message: Creation of dynamic property CI_Loader::$User_model is deprecated
Filename: core/Loader.php
Line Number: 925
Severity: 8192
Message: Creation of dynamic property CI_Loader::$data is deprecated
Filename: core/Loader.php
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Message: Creation of dynamic property CI_Loader::$pagination is deprecated
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Published : 05 Oct 2020
Drug Name: BNT-162b2
Pfizer and BioNTech have started participant enrolment in a Phase III clinical trial of their Covid-19 vaccine candidate in South Africa.
The Phase III programme is set to enrol about 44,000 participants globally, with a focus on trial population diversity, including those with chronic, stable HIV, hepatitis C, or hepatitis B infection.
Designed to assess the safety and efficacy of the vaccine candidate, the trial will involve nearly 800 subjects at four sites across Gauteng, Limpopo, and the Western Cape in South Africa.
The South African Health Products Regulatory Authority (Sahpra) granted regulatory approval for the trial on 22 September 2020.
Dr. Essack Mitha has been appointed as the trial’s national principal investigator.
Dr Mitha said: “We are proud and excited to be allowed to take part in this global research effort. South African patients will play a critical role in the fight against Covid-19.
“We are confident that the South African sites will contribute high-quality data to this ground-breaking study, and that medical science will prevail in this pandemic.”
Pfizer and BioNtech have already enrolled more than 35,000 volunteers worldwide, following the US Food and Drug Administration (FDA) approval.
Pfizer South Africa medical director Dr Bha Ndungane-Tlakula said: “At Pfizer, we are proud to be bringing this important study to the country, and to the African Continent, to add to the growing knowledge of this virus so we can find a lasting and sustainable solution to end this pandemic.”
Last month, Pfizer said that Phase III trial participants were experiencing mild-to-moderate side effects with its investigational Covid-19 vaccine candidate.
On an investor conference call, the company executives noted that more than 12,000 study participants had received a second dose of the vaccine candidate.
Pfizer added that it was continuously analyzing the safety and tolerability of the candidate in its trial.
Source: GlobalData.com
